Enzyme-alterable alkylating agents. II. Clinical evaluation of N, N′-bis[(2-chloroethylthio)acetyl]-1,2-ethylenediamine (S-46)
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چکیده
منابع مشابه
Syntheses, Characterization and Solvatochromism Study of Heteroleptic Chelated Copper(II) Complexes Containing N,N- dibezyl Substituted Ethylenediamine and Acetylacetonate Ligands
A series of new heteroleptic chelated copper(II) complexes that encompass N,N-dibezyl substituted derivative of ethylenediamine (X-diamine) and acetylacetonate (acac) were prepared. The IR and electronic absorption spectra and the molar conductivity of the complexes are presented and discussed. The molar conductivity values of the complexes in different solvents reveals a predominance of elec...
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Antioxidants act as free radical scavengers in the oxidation processes. Thus, they will certainly play diverse roles in the biological systems and the therapy of a wide variety of diseases. Regarding this fact, in the present study, we synthesized two new salen ligand compounds by the condensation of ethylendiamine and salicylaldehyde derivatives in excellent yields.The structures of ...
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Bis(μ-N,N-dimethyldithiocarbamato-κ3 S,S′:S)bis[(N,N-dimethyldithiocarbamato-κ2 S,S′)copper(II)]
In the centrosymmetric dimeric title compound, [Cu(2)(C(3)H(6)NS(2))(4)], the Cu(II) atom is five-coordinate in a square-pyramidal environment. The basal coordination positions are occupied by four S atoms from two dimethyl-dithio-carbamate ligands and the apical coordination position is occupied by an S atom also bonded to the other Cu atom.
متن کاملBis(N-butyl-N-ethyldithiocarbamato-κ2 S,S′)nickel(II)
The dithio-carbamate anions in the title compound, [Ni(C(7)H(14)NS(2))(2)], chelate to the Ni(II) atom, which is four-coordinate in a square-planar geometry. The Ni(II) atom lies on a center of inversion.
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ژورنال
عنوان ژورنال: Cancer
سال: 1962
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(196209/10)15:5<1056::aid-cncr2820150522>3.0.co;2-u